General Control Nonderepressible 2 and ATF4 Direct Liver Genes during Asparaginase Treatment in Mice
Asparaginase (ASNase) treatment results in the synthesis of some factors such as ATF4. The eIF2-ATF4 pathway is essential for cell survival during amino acid starvation conditions. Activation of the AAR in the liver requires the eIF2 kinase called general control nonderepressible 2 kinase (GCN2). To...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
College of Veterinary Medicine
2018-12-01
|
| Series: | Al-Qadisiyah Journal of Veterinary Medicine Sciences |
| Online Access: | http://www.qu.edu.iq/journalvm/index.php/vm_journal/article/view/516 |