DDX56 inhibits PRV replication through regulation of IFN-β signaling pathway by targeting cGAS

DDX56 inhibits PRV replication through regulation of IFN-β signaling pathway by targeting cGAS

Pseudorabies virus (PRV) is an agent of Aujeszky's disease, and causes great economic losses to pig farming. Re-outburst of pseudorabies implies that new control measures are urgently needed. We show here that DDX56 possesses the ability to inhibit PRV replication in vitro, which may be an impo...

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Bibliographic Details
Main Authors: Jingying Xie, Xiangrong Li, Shunyu Yang, Zhenfang Yan, Lei Chen, Yanmei Yang, Dianyu Li, Xiangbo Zhang, Ruofei Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Microbiology
Subjects:
pseudorabies virus
DDX56 protein
innate immune response
IFN-β
cGAS
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.932842/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.932842/full

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