Association between SMAD3 gene polymorphisms and osteoarthritis risk: a systematic review and meta-analysis

Abstract Objective Several studies have been performed to investigate the association between SMAD3 gene polymorphism and osteoarthritis (OA), but the results were inconclusive. This study aims to determine whether SMAD3 polymorphism is associated with risk of OA. Method A comprehensive literature s...

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Bibliographic Details
Main Authors: Jian-qiao Hong, Yang-xin Wang, Si-hao Li, Guang-yao Jiang, Bin Hu, Yu-te Yang, Jia-hong Meng, Shi-gui Yan
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13018-018-0939-2