Decreased expression of BRCA1 in SK-BR-3 cells is the result of aberrant activation of the GABP Beta promoter by an NRF-1-containing complex

<p>Abstract</p> <p>Background</p> <p>BRCA1 has recently been identified as a potential regulator of mammary stem/progenitor cell differentiation, and this function may explain the high prevalence of breast cancer in <it>BRCA1 </it>mutation carriers, as well...

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Bibliographic Details
Main Authors: MacDonald Gwen, Thompson Crista, Mueller Christopher R
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/62