<i>PPP3R1</i> Promotes MSCs Senescence by Inducing Plasma Membrane Depolarization and Increasing Ca<sup>2+</sup> Influx

Aging of mesenchymal stem cells(MSCs) has been widely reported to be strongly associated with aging-related diseases, including osteoporosis (OP). In particular, the beneficial functions of mesenchymal stem cells decline with age, limiting their therapeutic efficacy in age-related bone loss diseases...

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Bibliographic Details
Main Authors: Molin Li, Weimin Gong, Jie Chen, Yining Zhang, Yufei Ma, Xiaolin Tu
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/5/4421