Central proliferation and neurogenesis is impaired in type 2 diabetes and prediabetes animal models.

Type 2 diabetes (T2D) is an important risk factor to suffer dementia, including Alzheimer's disease (AD), and some neuropathological features observed in dementia could be mediated by T2D metabolic alterations. Since brain atrophy and impaired neurogenesis have been observed both T2D and AD we...

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Main Authors: Juan Jose Ramos-Rodriguez, Sara Molina-Gil, Oscar Ortiz-Barajas, Margarita Jimenez-Palomares, German Perdomo, Irene Cozar-Castellano, Alfonso Maria Lechuga-Sancho, Monica Garcia-Alloza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089229&type=printable