MULTIFACTORIAL PATHOGENESIS OF OSTEOPOROSIS AND THE ROLE OF GENES OF CANONICAL WNT-SIGNALING PATHWAY

Nowadays, multifactorial nature of osteoporosis does not raise any doubts. Besides, it should be noted that about 90% disease cases are determined genetically. In 1990-s a number of candidate genes mutations were established which increase the risk of osteoporosis development. VDR, ESR1, ESR2, COLIA...

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Bibliographic Details
Main Author: E A Mailyan
Format: Article
Language:English
Published: Endocrinology Research Centre 2015-12-01
Series:Остеопороз и остеопатии
Subjects:
Online Access:https://endojournals.ru/index.php/osteo/article/view/8910