Impact of radiation on host immune system in patients treated with chemoradiotherapy and durvalumab consolidation for unresectable locally advanced non-small cell lung cancer

Impact of radiation on host immune system in patients treated with chemoradiotherapy and durvalumab consolidation for unresectable locally advanced non-small cell lung cancer

BackgroundThe optimal modalities of radiotherapy when combining concurrent chemoradiation (CCRT) and immunotherapy (IO) for locally advanced non-small cell lung cancer (LA-NSCLC) remain to be determined. The aim of this study was to investigate the impact of radiation on different immune structures...

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Bibliographic Details
Main Authors: Corentin Pasquier, Léonor Chaltiel, Carole Massabeau, Audrey Rabeau, Louisiane Lebas, Amélie Lusque, Jean-Sébastien Texier, Elizabeth Cohen-Jonathan Moyal, Julien Mazières, Jonathan Khalifa
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
radiotherapy
immunotherapy
non-small cell lung cancer (NSCLC)
tumor-draining lymph nodes (TDLN)
EDRIC
lymphopenia
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1186479/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1186479/full

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