Extensive analysis of D-J-C arrangements allows the identification of different mechanisms enhancing the diversity in sheep T cell receptor β-chain repertoire

<p>Abstract</p> <p>Background</p> <p>In most species of mammals, the <it>TRB </it>locus has the common feature of a library of <it>TRBV </it>genes positioned at the 5'- end of two in tandem aligned D-J-C gene clusters, each composed of a sin...

Full description

Bibliographic Details
Main Authors: Ciccarese Salvatrice, Antonacci Rachele, Di Tommaso Silvia, Massari Serafina
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/11/3