Intrathecal dexmedetomidine attenuates mechanical allodynia through the downregulation of brain-derived neurotrophic factor in a mild traumatic brain injury rat model

Background This study evaluated the effects of dexmedetomidine and propofol on brain-derived neurotrophic factor level in the cerebrospinal fluid (c-BDNF) and mechanical allodynia in a mild traumatic brain injury (TBI) rat model. Methods After fixing the rat’s skull on a stereotactic frame under gen...

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Bibliographic Details
Main Authors: Soeun Jeon, Jiseok Baik, Jisu Kim, Jiyoon Lee, Wangseok Do, Eunsoo Kim, Hyeon Jeong Lee, Haekyu Kim
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2023-02-01
Series:Korean Journal of Anesthesiology
Subjects:
Online Access:http://ekja.org/upload/pdf/kja-22209.pdf