Electrochemical and theoretical studies of the interaction between anticancer drug ponatinib and dsDNA

Abstract In this study, electrochemical and theoretical studies were performed to explain the interaction mechanism between ponatinib (PNT), a third generation tyrosine kinase inhibitor, and dsDNA. The electrochemical part was conducted in phosphate-buffered saline (PBS) at physiological pH of 7.4 a...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Sylwia Smarzewska, Anna Ignaczak, Kamila Koszelska
التنسيق: مقال
اللغة:English
منشور في: Nature Portfolio 2024-01-01
سلاسل:Scientific Reports
الوصول للمادة أونلاين:https://doi.org/10.1038/s41598-024-52609-z