Vascular Injury in the Zebrafish Tail Modulates Blood Flow and Peak Wall Shear Stress to Restore Embryonic Circular Network

Vascular Injury in the Zebrafish Tail Modulates Blood Flow and Peak Wall Shear Stress to Restore Embryonic Circular Network

Mechano-responsive signaling pathways enable blood vessels within a connected network to structurally adapt to partition of blood flow between organ systems. Wall shear stress (WSS) modulates endothelial cell proliferation and arteriovenous specification. Here, we study vascular regeneration in a ze...

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Bibliographic Details
Main Authors: Kyung In Baek, Shyr-Shea Chang, Chih-Chiang Chang, Mehrdad Roustaei, Yichen Ding, Yixuan Wang, Justin Chen, Ryan O'Donnell, Hong Chen, Julianne W. Ashby, Xiaolei Xu, Julia J. Mack, Susana Cavallero, Marcus Roper, Tzung K. Hsiai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
biophysics
peak wall shear stress
Notch-ephrinb2 signaling
vascular loop formation
vascular injury and repair
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.841101/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.841101/full

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