Modulation of Early Neutrophil Granulation: The Circulating Tumor Cell-Extravesicular Connection in Pancreatic Ductal Adenocarcinoma

Modulation of Early Neutrophil Granulation: The Circulating Tumor Cell-Extravesicular Connection in Pancreatic Ductal Adenocarcinoma

Tumor cells dissociate from the primary site and enter into systemic circulation (circulating tumor cells, CTCs) either alone or as tumor microemboli (clusters); the latter having an increased predisposition towards forming distal metastases than single CTCs. The formation of clusters is, in part, c...

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Bibliographic Details
Main Authors: Harrys Kishore Charles Jacob, John Lalith Charles Richard, Rossana Signorelli, Tyler Kashuv, Shweta Lavania, Utpreksha Vaish, Ranjitha Boopathy, Ashley Middleton, Melinda Minucci Boone, Ramakrishnan Sundaram, Vikas Dudeja, Ashok Kumar Saluja
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
pancreatic cancer
extracellular vesicles
neutrophil degranulation
granule mobilization
reteplase activity
circulating tumor cells
Online Access:https://www.mdpi.com/2072-6694/13/11/2727

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https://www.mdpi.com/2072-6694/13/11/2727

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