Statistical power in COVID-19 case-control host genomic study design

Statistical power in COVID-19 case-control host genomic study design

Abstract The identification of genetic variation that directly impacts infection susceptibility to SARS-CoV-2 and disease severity of COVID-19 is an important step towards risk stratification, personalized treatment plans, therapeutic, and vaccine development and deployment. Given the importance of...

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Bibliographic Details
Main Authors: Yu-Chung Lin, Jennifer D. Brooks, Shelley B. Bull, France Gagnon, Celia M. T. Greenwood, Rayjean J. Hung, Jerald Lawless, Andrew D. Paterson, Lei Sun, Lisa J. Strug, On behalf of the Genetic Epidemiology Committee of the Canadian COVID Genomics Network (CanCOGeN) HostSeq Project
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Genome Medicine
Subjects:
Genetic epidemiology
Statistical genetics
Study design
Genome-wide association studies
Online Access:https://doi.org/10.1186/s13073-020-00818-2

Internet

https://doi.org/10.1186/s13073-020-00818-2

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