Emerging complexities of APOBEC3G action on immunity and viral fitness during HIV infection and treatment
<p>Abstract</p> <p>The enzyme APOBEC3G (A3G) mutates the human immunodeficiency virus (HIV) genome by converting deoxycytidine (dC) to deoxyuridine (dU) on minus strand viral DNA during reverse transcription. A3G restricts viral propagation by degrading or incapacitating the coding...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-04-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/9/1/35 |