Emerging complexities of APOBEC3G action on immunity and viral fitness during HIV infection and treatment

Emerging complexities of APOBEC3G action on immunity and viral fitness during HIV infection and treatment

<p>Abstract</p> <p>The enzyme APOBEC3G (A3G) mutates the human immunodeficiency virus (HIV) genome by converting deoxycytidine (dC) to deoxyuridine (dU) on minus strand viral DNA during reverse transcription. A3G restricts viral propagation by degrading or incapacitating the coding...

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Bibliographic Details
Main Authors:	Monajemi Mahdis, Woodworth Claire F, Benkaroun Jessica, Grant Michael, Larijani Mani
Format:	Article
Language:	English
Published:	BMC 2012-04-01
Series:	Retrovirology
Online Access:	http://www.retrovirology.com/content/9/1/35

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