Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis

Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis

Abstract Background Acute pancreatitis is the sudden inflammation of the pancreas. Severe cases of acute pancreatitis are potentially fatal and have no specific treatment available. Premature trypsinogen activation could initiate acute pancreatitis. However, the mechanism underlying premature trypsi...

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Bibliographic Details
Main Authors: Juan Xiao, Wenying Zeng, Pengcheng Zhang, Yuan Zhou, Qiangqiang Fang
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Molecular Medicine
Subjects:
Acid ceramidase
MIB1
Trypsinogen
Pyruvate kinase
Acute pancreatitis
Online Access:https://doi.org/10.1186/s10020-022-00538-w

Internet

https://doi.org/10.1186/s10020-022-00538-w

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