Amelioration of functional and histopathological consequences after spinal cord injury through phosphodiesterase 4D (PDE4D) inhibition

Amelioration of functional and histopathological consequences after spinal cord injury through phosphodiesterase 4D (PDE4D) inhibition

Spinal cord injury (SCI) is a life-changing event that severely impacts the patient's quality of life. Modulating neuroinflammation, which exacerbates the primary injury, and stimulating neuro-regenerative repair mechanisms are key strategies to improve functional recovery. Cyclic adenosine mon...

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Bibliographic Details
Main Authors: Melissa Schepers, Sven Hendrix, Femke Mussen, Elise van Breedam, Peter Ponsaerts, Stefanie Lemmens, Niels Hellings, Roberta Ricciarelli, Ernesto Fedele, Olga Bruno, Chiara Brullo, Jos Prickaerts, Jana Van Broeckhoven, Tim Vanmierlo
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Neurotherapeutics
Subjects:
Spinal cord injury
Phosphodiesterase 4
cAMP
Neuroinflammation
Regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S1878747924000588

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http://www.sciencedirect.com/science/article/pii/S1878747924000588

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