Macrophage-derived exosome promotes regulatory T cell differentiation in malignant pleural effusion

Macrophage-derived exosome promotes regulatory T cell differentiation in malignant pleural effusion

IntroductionTumor-associated macrophages are one of the key components of the tumor microenvironment. The immunomodulatory activity and function of macrophages in malignant pleural effusion (MPE), a special tumor metastasis microenvironment, have not been clearly defined.MethodsMPE-based single-cell...

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Bibliographic Details
Main Authors: Ming-Ming Shao, Xue-Bin Pei, Qing-Yu Chen, Feng Wang, Zhen Wang, Kan Zhai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
malignant pleural effusion
macrophages
exosomes
miR-4443
Treg
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1161375/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1161375/full

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