Poloxamer [corrected] 188 has a deleterious effect on dystrophic skeletal muscle function.

Duchenne muscular dystrophy (DMD) is an X-linked, fatal muscle wasting disease for which there is currently no cure and limited palliative treatments. Poloxomer 188 (P188) is a tri-block copolymer that has been proposed as a potential treatment for cardiomyopathy in DMD patients. Despite the reporte...

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Bibliographic Details
Main Authors: Rebecca L Terry, Hannah M Kaneb, Dominic J Wells
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3958340?pdf=render