Utility of the 13C‐pantoprazole breath test as a CYP2C19 phenotyping probe for children

Utility of the 13C‐pantoprazole breath test as a CYP2C19 phenotyping probe for children

Abstract The 13C‐pantoprazole breath test (PAN‐BT) is a safe, noninvasive, in vivo CYP2C19 phenotyping probe for adults. Our objective was to evaluate PAN‐BT performance in children, with a focus on discriminating individuals who, according to guidelines from the Clinical Pharmacology Implementation...

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Bibliographic Details
Main Authors: Keith Feldman, Gregory L. Kearns, Robin E. Pearce, Susan M. Abdel‐Rahman, James Steven Leeder, Alec Friesen, Vincent S. Staggs, Andrea Gaedigk, Jaylene Weigel, Valentina Shakhnovich
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13232

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https://doi.org/10.1111/cts.13232

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