Exosomal lncRNA UCA1 Derived From Pancreatic Stellate Cells Promotes Gemcitabine Resistance in Pancreatic Cancer via the SOCS3/EZH2 Axis
ObjectivePancreatic cancer is associated with poor prognosis and dismal survival rates. This study aims to investigate roles of lncRNA UCA1-loaded exosomes secreted by pancreatic stellate cells (PSCs) in Gemcitabine (Gem) resistance of pancreatic cancer under hypoxia, which involves the methylation...
| Main Authors: | , , |
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| 格式: | 文件 |
| 语言: | English |
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Frontiers Media S.A.
2021-11-01
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| 丛编: | Frontiers in Oncology |
| 主题: | |
| 在线阅读: | https://www.frontiersin.org/articles/10.3389/fonc.2021.671082/full |