Integrin Regulated Autoimmune Disorders: Understanding the Role of Mechanical Force in Autoimmunity

Integrin Regulated Autoimmune Disorders: Understanding the Role of Mechanical Force in Autoimmunity

The pathophysiology of autoimmune disorders is multifactorial, where immune cell migration, adhesion, and lymphocyte activation play crucial roles in its progression. These immune processes are majorly regulated by adhesion molecules at cell–extracellular matrix (ECM) and cell–cell junctions. Integr...

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Bibliographic Details
Main Authors: Souradeep Banerjee, Ritika Nara, Soham Chakraborty, Debojyoti Chowdhury, Shubhasis Haldar
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
integrin
autoimmune diseases
mechanical force
focal adhesion
tissue stiffness
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.852878/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.852878/full

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