Scavenger receptor BI promotes cytoplasmic accumulation of lipoproteins in clear-cell renal cell carcinoma

Clear-cell renal cell carcinomas (ccRCCs) are characterized by inactivation of the von Hippel-Lindau (VHL) gene and intracellular lipid accumulation by unknown pathomechanisms. The immunochemical analysis of 356 RCCs revealed high abundance of apoA-I and apoB, as well as scavenger receptor BI (SR-BI...

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Bibliographic Details
Main Authors: Srividya Velagapudi, Peter Schraml, Mustafa Yalcinkaya, Hella A. Bolck, Lucia Rohrer, Holger Moch, Arnold von Eckardstein
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520309196