Downregulation of MTHFD2 Inhibits Proliferation and Enhances Chemosensitivity in Hepatocellular Carcinoma via PI3K/AKT Pathway

Background: Despite the substantial impact of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) on cancer progression, its significance in the regulation of hepatocellular carcinoma (HCC) cell proliferation and chemosensitivity remains poorly defined. Methods: We evaluated MTHFD2 expression in a to...

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Main Authors: Jie Wang, Ze Yu, Yixiao Jiang, Ting Le, Yixin Wu, Ziqi Li, Guoqiang Zhang, Feiyue Wu, Haijie Ma
格式: 文件
语言:English
出版: IMR Press 2024-01-01
丛编:Frontiers in Bioscience-Landmark
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在线阅读:https://www.imrpress.com/journal/FBL/29/1/10.31083/j.fbl2901035