Apolipoprotein L1 (APOL1) Variants (Vs) a Possible Link between Heroin-associated Nephropathy (HAN) and HIV-associated Nephropathy (HIVAN)

Apolipoprotein L1 (APOL1) Variants (Vs) a Possible Link between Heroin-associated Nephropathy (HAN) and HIV-associated Nephropathy (HIVAN)

In 1970s, Heroin-associated Nephropathy (HAN), one form of focal and segmental glomerulosclerosis (FSGS), was a predominant cause of End-stage Kidney Disease (ESKD) in African-Americans (AAs). In 1980s, with the surge of Acquired Immune Deficiency Syndrome (AIDS) in AAs, HAN more or less disappeare...

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Bibliographic Details
Main Authors: Xiqian eLan, T. K.S. Rao, Praveen N Chander, Karl eSkorecki, Pravin C Singhal
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Microbiology
Subjects:
Podocytes
Opiates
APOL1
HIV-associated nephropathy
Heroin nephropathy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00571/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00571/full

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