Polygenic Risk Score Impact on Susceptibility to Age-Related Macular Degeneration in Polish Patients

Polygenic Risk Score Impact on Susceptibility to Age-Related Macular Degeneration in Polish Patients

Age-related macular degeneration (AMD) is a common retina degenerative disease with a complex genetic and environmental background. This study aimed to determine the polygenic risk score (PRS) stratification between the AMD case and control patients. The PRS model was established on the targeted seq...

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Bibliographic Details
Main Authors: Anna Wąsowska, Sławomir Teper, Ewa Matczyńska, Przemysław Łyszkiewicz, Adam Sendecki, Anna Machalińska, Edward Wylęgała, Anna Boguszewska-Chachulska
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Journal of Clinical Medicine
Subjects:
age-related macular degeneration
AMD genetics
polygenic model
polygenic risk score
susceptibility variants
Online Access:https://www.mdpi.com/2077-0383/12/1/295

Internet

https://www.mdpi.com/2077-0383/12/1/295

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