Staphylococcus aureus surface protein SdrE binds complement regulator factor H as an immune evasion tactic.

Staphylococcus aureus surface protein SdrE binds complement regulator factor H as an immune evasion tactic.

Similar to other highly successful invasive bacterial pathogens, Staphylococcus aureus recruits the complement regulatory protein factor H (fH) to its surface to inhibit the alternative pathway of complement. Here, we report the identification of the surface-associated protein SdrE as a fH-binding p...

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Bibliographic Details
Main Authors: Julia A Sharp, Charlene G Echague, Pamela S Hair, Michael D Ward, Julius O Nyalwidhe, Joan A Geoghegan, Timothy J Foster, Kenji M Cunnion
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3364985?pdf=render

Internet

http://europepmc.org/articles/PMC3364985?pdf=render

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