Staphylococcus aureus surface protein SdrE binds complement regulator factor H as an immune evasion tactic.
Similar to other highly successful invasive bacterial pathogens, Staphylococcus aureus recruits the complement regulatory protein factor H (fH) to its surface to inhibit the alternative pathway of complement. Here, we report the identification of the surface-associated protein SdrE as a fH-binding p...
Main Authors: | Julia A Sharp, Charlene G Echague, Pamela S Hair, Michael D Ward, Julius O Nyalwidhe, Joan A Geoghegan, Timothy J Foster, Kenji M Cunnion |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3364985?pdf=render |
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