Indoxyl sulfate induces apoptosis in mononuclear blood cells via mitochondrial pathway

Abstract The consequence of chronic kidney disease is the accumulation of metabolic products called uremic toxins in the body. Indoxyl sulfate (IS) is a toxin with a high affinity for proteins. This study focuses on the deleterious effect of IS, especially apoptosis induction, in mononuclear blood c...

Full description

Bibliographic Details
Main Authors: Anna Pieniazek, Joanna Bernasinska-Slomczewska, Pawel Hikisz
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40824-z