Osteostatin Inhibits M-CSF+RANKL-Induced Human Osteoclast Differentiation by Modulating NFATc1

Osteostatin Inhibits M-CSF+RANKL-Induced Human Osteoclast Differentiation by Modulating NFATc1

Parathyroid hormone-related protein (PTHrP) C-terminal peptides regulate the metabolism of bone cells. PHTrP [107–111] (osteostatin) promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis. In addition to its positive effects on osteoblasts, osteosta...

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Bibliographic Details
Main Authors: Lidia Ibáñez, Josep Nácher-Juan, María Carmen Terencio, María Luisa Ferrándiz, María José Alcaraz
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
PTHrP C-terminal peptides
osteostatin
bone
osteoclast
NFATc1
Online Access:https://www.mdpi.com/1422-0067/23/15/8551

Internet

https://www.mdpi.com/1422-0067/23/15/8551

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