The Role of Common Solvents against Pseudomonas aeruginosa-Induced Pathogenicity in a Murine Burn Site Infection Model

ABSTRACT Dimethyl sulfoxide (DMSO) and polyethylene glycols (PEGs) are frequently used as potent excipients in pharmaceutical formulations. However, these agents also have an interesting antimicrobial and anti-inflammatory profile that could interfere with the efficacy testing of anti-infective comp...

Full description

Bibliographic Details
Main Authors: Vijay K. Singh, Marianna Almpani, Laurence G. Rahme
Format: Article
Language:English
Published: American Society for Microbiology 2021-09-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.00233-21