Therapeutic Salivary Monitoring of Perampanel in Patients with Epilepsy Using a Volumetric Absorptive Microsampling Technique

Therapeutic Salivary Monitoring of Perampanel in Patients with Epilepsy Using a Volumetric Absorptive Microsampling Technique

The objective of this study was to validate a novel assay using the volumetric absorptive microsampling (VAMS) technique combined with liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) for the determination of the antiseizure medication perampanel in saliva and its clinical applic...

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Bibliographic Details
Main Authors: Michela Palmisani, Elena Tartara, Cecilie Johannessen Landmark, Francesca Crema, Valentina De Giorgis, Costanza Varesio, Cinzia Fattore, Paola Rota, Emilio Russo, Valentina Franco
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceutics
Subjects:
perampanel
LC-MS/MS
therapeutic drug monitoring
saliva
volumetric absorptive microsampling
Online Access:https://www.mdpi.com/1999-4923/15/8/2030

Internet

https://www.mdpi.com/1999-4923/15/8/2030

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