Calcium Delivery by Electroporation Induces In Vitro Cell Death through Mitochondrial Dysfunction without DNA Damages

Calcium Delivery by Electroporation Induces In Vitro Cell Death through Mitochondrial Dysfunction without DNA Damages

Adolescent cancer survivors present increased risks of developing secondary malignancies due to cancer therapy. Electrochemotherapy is a promising anti-cancer approach that potentiates the cytotoxic effect of drugs by application of external electric field pulses. Clinicians proposed to associate el...

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Bibliographic Details
Main Authors: Laure Gibot, Audrey Montigny, Houda Baaziz, Isabelle Fourquaux, Marc Audebert, Marie-Pierre Rols
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
calcium electroporation
electrochemotherapy
spheroids
magnesium
genotoxicity
mitochondria
Online Access:https://www.mdpi.com/2072-6694/12/2/425

Internet

https://www.mdpi.com/2072-6694/12/2/425

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