The FBW7-MCL-1 axis is key in M1 and M2 macrophage-related colon cancer cell progression: validating the immunotherapeutic value of targeting PI3Kγ

Cancer treatment: turning the tide against colon cancer Drugs that target a specific subset of immune cells could render colorectal tumors more susceptible to immunological destruction by the host. The cellular composition of a tumor profoundly affects the odds of progression or survival, and some i...

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Bibliographic Details
Main Authors: Yeo Song Lee, Su Jeong Song, Hye Kyung Hong, Bo Young Oh, Woo Yong Lee, Yong Beom Cho
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-020-0436-7