Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing

Abstract Central carbon metabolism is highly conserved across microbial species, but can catalyze very different pathways depending on the organism and their ecological niche. Here, we study the dynamic reorganization of central metabolism after switches between the two major opposing pathway config...

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Bibliographic Details
Main Authors: Severin Josef Schink, Dimitris Christodoulou, Avik Mukherjee, Edward Athaide, Viktoria Brunner, Tobias Fuhrer, Gary Andrew Bradshaw, Uwe Sauer, Markus Basan
Format: Article
Language:English
Published: Springer Nature 2022-01-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.202110704