QSAR modelling to predict structural features of certain sulfonamide as Urokinase-type Plasminogen Activator inhibitors

QSAR modelling to predict structural features of certain sulfonamide as Urokinase-type Plasminogen Activator inhibitors

The serine hydrolase family includes serine proteases. It is essential for hydrolyzing protein peptide bonds and breaking them. The urokinase-type plasminogen activator (uPA) selectively binds to the uPAR on numerous cell types, including cancer cells. Pericellular proteolysis of cell-bound proteins...

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Bibliographic Details
Main Authors: Rahul D. Jawarkar, Magdi E.A. Zaki, Sami A. Al-Hussain, Abdullah Yahya Abdullah Alzahrani, Long Chiau Ming, Abdul Samad, Rahul G. Ingle, Suraj N. Mali
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Chemical Physics Impact
Subjects:
Urokinase-type plasminogen activator inhibitors
QSAR
Pharmacophoric features
Online Access:http://www.sciencedirect.com/science/article/pii/S2667022424000884

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http://www.sciencedirect.com/science/article/pii/S2667022424000884

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