Antimicrobials in polymethylmethacrylate: from prevention to prosthetic joint infection treatment: basic principles and risk of resistance

Antimicrobials in polymethylmethacrylate: from prevention to prosthetic joint infection treatment: basic principles and risk of resistance

Abstract Background Excellent revisions about antibiotic-loaded bone cement (ALBC) have been recently published. In the present article, we review the principles and limitations of local antibiotic delivery in the context of recent advances in the pathogenesis of prosthetic joint infections (PJI), w...

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Bibliographic Details
Main Authors: Marta Sabater-Martos, Miguel A. Verdejo, Laura Morata, Ernesto Muñoz-Mahamud, Ernesto Guerra-Farfan, Juan C. Martinez-Pastor, Alex Soriano
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Arthroplasty
Subjects:
Antibiotic-loaded bone cement
Pharmacokinetics
Antibiotic prophylaxis
Spacers
Antibiotic resistance
Online Access:https://doi.org/10.1186/s42836-023-00166-7

Internet

https://doi.org/10.1186/s42836-023-00166-7

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