Revealing the Mutation Patterns of Drug-Resistant Reverse Transcriptase Variants of Human Immunodeficiency Virus through Proteochemometric Modeling

Revealing the Mutation Patterns of Drug-Resistant Reverse Transcriptase Variants of Human Immunodeficiency Virus through Proteochemometric Modeling

Drug-resistant cases of human immunodeficiency virus (HIV) nucleoside reverse transcriptase inhibitors (NRTI) are constantly accumulating due to the frequent mutations of the reverse transcriptase (RT). Predicting the potential drug resistance of HIV-1 NRTIs could provide instructions for the proper...

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Bibliographic Details
Main Authors: Jingxuan Qiu, Xinxin Tian, Jiangru Liu, Yulong Qin, Junjie Zhu, Dongpo Xu, Tianyi Qiu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
HIV
reverse transcriptase
drug resistance
computational model
Online Access:https://www.mdpi.com/2218-273X/11/9/1302

Internet

https://www.mdpi.com/2218-273X/11/9/1302

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