DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation
Enhanced glycolysis is a hallmark of breast cancer. In cancer cells, the high glycolytic flux induces carbonyl stress, a damaging condition in which the increase of reactive carbonyl species makes DNA, proteins, and lipids more susceptible to glycation. Together with glucose, methylglyoxal (MGO), a...
Hlavní autoři: | , , , , , , , , , , , |
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Médium: | Článek |
Jazyk: | English |
Vydáno: |
MDPI AG
2020-08-01
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Edice: | Cells |
Témata: | |
On-line přístup: | https://www.mdpi.com/2073-4409/9/9/1968 |