DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation

Enhanced glycolysis is a hallmark of breast cancer. In cancer cells, the high glycolytic flux induces carbonyl stress, a damaging condition in which the increase of reactive carbonyl species makes DNA, proteins, and lipids more susceptible to glycation. Together with glucose, methylglyoxal (MGO), a...

詳細記述

書誌詳細
主要な著者: Domenica Scumaci, Erika Olivo, Claudia Vincenza Fiumara, Marina La Chimia, Maria Teresa De Angelis, Sabrina Mauro, Giosuè Costa, Francesca Alessandra Ambrosio, Stefano Alcaro, Valter Agosti, Francesco Saverio Costanzo, Giovanni Cuda
フォーマット: 論文
言語:English
出版事項: MDPI AG 2020-08-01
シリーズ:Cells
主題:
オンライン・アクセス:https://www.mdpi.com/2073-4409/9/9/1968

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