Folate-Functionalization Enhances Cytotoxicity of Multivalent DNA Nanocages on Triple-Negative Breast Cancer Cells

Folate-Functionalization Enhances Cytotoxicity of Multivalent DNA Nanocages on Triple-Negative Breast Cancer Cells

DNA is an excellent programmable polymer for the generation of self-assembled multivalent nanostructures useful for biomedical applications. Herein, we developed (i) folate-functionalized nanocages (Fol-NC), very efficiently internalized by tumor cells overexpressing the α isoform of the folate rece...

Full description

Bibliographic Details
Main Authors: Valeria Unida, Giulia Vindigni, Sofia Raniolo, Carmine Stolfi, Alessandro Desideri, Silvia Biocca
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
DNA nanostructure
AS1411
miR-21
folate receptor
nucleolin
doxorubicin delivery
Online Access:https://www.mdpi.com/1999-4923/14/12/2610

Internet

https://www.mdpi.com/1999-4923/14/12/2610

Similar Items