Translational Capacity of a Cell Is Determined during Transcription Elongation via the Ccr4-Not Complex

The current understanding of gene expression considers transcription and translation to be independent processes. Challenging this notion, we found that translation efficiency is determined during transcription elongation through the imprinting of mRNAs with Not1, the central scaffold of the Ccr4-No...

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Bibliographic Details
Main Authors: Ishaan Gupta, Zoltan Villanyi, Sari Kassem, Christopher Hughes, Olesya O. Panasenko, Lars M. Steinmetz, Martine A. Collart
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471630482X