Characterization of the Interaction Between SARS-CoV-2 Membrane Protein (M) and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target

Characterization of the Interaction Between SARS-CoV-2 Membrane Protein (M) and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target

SARS-CoV-2 is an emerging virus from the Coronaviridae family and is responsible for the ongoing COVID-19 pandemic. In this work, we explored the previously reported SARS-CoV-2 structural membrane protein (M) interaction with human Proliferating Cell Nuclear Antigen (PCNA). The M protein is responsi...

Full description

Bibliographic Details
Main Authors: Érika Pereira Zambalde, Isadora Carolina Betim Pavan, Mariana Camargo Silva Mancini, Matheus Brandemarte Severino, Orlando Bonito Scudero, Ana Paula Morelli, Mariene Ribeiro Amorim, Karina Bispo-dos-Santos, Mariana Marcela Góis, Daniel A. Toledo-Teixeira, Pierina Lorencini Parise, Thais Mauad, Marisa Dolhnikoff, Paulo Hilário Nascimento Saldiva, Henrique Marques-Souza, José Luiz Proenca-Modena, Armando Morais Ventura, Fernando Moreira Simabuco
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
SARS-CoV-2
PCNA
M protein
viral-host interaction
DNA damage
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.849017/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.849017/full

Similar Items