Immune effector mechanisms of the nitric oxide pathway in malaria: cytotoxicity versus cytoprotection
Nitric oxide (NO) is thought to be an important mediator and critical signaling molecule for malaria immunopathology; it is also a target for therapy and for vaccine. Inducible nitric oxide synthase (iNOS) is synthesized by a number of cell types under inflammatory conditions. The most relevant know...
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Format: | Article |
Language: | English |
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Elsevier
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Series: | Brazilian Journal of Infectious Diseases |
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000400014&lng=en&tlng=en |