Gonadal dysfunction in a man with Noonan syndrome from the LZTR1 variant: case report and review of literature

Gonadal dysfunction in a man with Noonan syndrome from the LZTR1 variant: case report and review of literature

Noonan syndrome (NS) is a genetic disorder characterized by multiple congenital defects caused by mutations in the RAS/mitogen-activated protein kinase pathway. Male fertility has been reported to be impaired in NS, but only a few studies have focused on fertility status in NS patients and underlyin...

Full description

Bibliographic Details
Main Authors: Francesca Orsolini, Luisa Pignata, Fulvia Baldinotti, Silvia Romano, Massimo Tonacchera, Domenico Canale
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Endocrinology
Subjects:
Noonan syndrome
gonadal function
fertility
LZTR1 variant
case report
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1354699/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2024.1354699/full

Similar Items