Magnetic vagus nerve stimulation alleviates myocardial ischemia-reperfusion injury by the inhibition of pyroptosis through the M2AChR/OGDHL/ROS axis in rats

Magnetic vagus nerve stimulation alleviates myocardial ischemia-reperfusion injury by the inhibition of pyroptosis through the M2AChR/OGDHL/ROS axis in rats

Abstract Background Myocardial ischemia-reperfusion (I/R) injury is accompanied by an imbalance in the cardiac autonomic nervous system, characterized by over-activated sympathetic tone and reduced vagal nerve activity. In our preceding study, we pioneered the development of the magnetic vagus nerve...

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Bibliographic Details
Main Authors: Yao Lu, Kaiyan Chen, Wei Zhao, Yan Hua, Siyuan Bao, Jian Zhang, Tianyu Wu, Gaoyuan Ge, Yue Yu, Jianfei Sun, Fengxiang Zhang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Nanobiotechnology
Subjects:
Myocardial I/R injury
Vagus nerve
mVNS
Pyroptosis
OGDHL
Online Access:https://doi.org/10.1186/s12951-023-02189-3

Internet

https://doi.org/10.1186/s12951-023-02189-3

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