Microgravity triggers ferroptosis and accelerates senescence in the MG-63 cell model of osteoblastic cells

Abstract In space, cells sustain strong modifications of their mechanical environment. Mechanosensitive molecules at the cell membrane regulate mechanotransduction pathways that induce adaptive responses through the regulation of gene expression, post-translational modifications, protein interaction...

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Bibliographic Details
Main Authors: Nancy Garbacki, Jérôme Willems, Thibaut Neutelings, Charles Lambert, Christophe Deroanne, Astrid Adrian, Markus Franz, Matthias Maurer, Philippe De Gieter, Betty Nusgens, Alain Colige
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:npj Microgravity
Online Access:https://doi.org/10.1038/s41526-023-00339-3