Andrographolide alleviates paraquat-induced acute lung injury by activating the Nrf2/HO-1 pathway

Objective(s): Paraquat (PQ), a highly effective and rapidly non-selective herbicide, mainly targets the lungs and causes acute lung injury (ALI). So far, the scarcity of effective drug candidates against PQ-induced ALI remains a big challenge. Andrographolide (Andro), with its anti-inflammatory and...

Full description

Bibliographic Details
Main Authors: Degang Zhang, Fengqin Shen, Shiting Ma, Suting Nan, Yanhong Ma, Lili Ren, Hao Li, Qin Yu
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_22227_f4f80b108618970480458867dee9760b.pdf