Recombinant pregnancy-specific glycoprotein-1-Fc reduces functional deficit in a mouse model of permanent brain ischaemia

Background: The well-characterised role of the immune system in acute ischaemic stroke has prompted the search for immunomodulatory therapies. Pregnancy-specific glycoproteins (PSGs) are a group of proteins synthesised by placental trophoblasts which show immunomodulatory properties. The aim of this...

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Bibliographic Details
Main Authors: Kyle Malone, Jennifer A. Shearer, John M. Williams, Anne C. Moore, Tom Moore, Christian Waeber
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354622000874